Sickle cell anemia has been a major killer of children and people from all around the world, over the years, lack of proper education on genotype to young people has caused a huge defect on several marriages, homes, family and household. Understanding our genotype before going into marriage is as important as the marriage, this is because the issues that springs out incompatible genotype are critical ones. ‘Wikipedia’, defines genotype as an organism’s complete set of heritable genes, or genes that can be passed down from parents to offspring. These genes helps encode the characteristics that are physically expressed in an organism, such as hair color, height, etc.
Simply put, genotype is a gene passed down from parent to their offspring. As it is, one of the major goal of a marriage is to give birth to offspring, knowing your genotype is a great determinant of the sort of genotype your offspring will have, some very few people are managing severe health complications due to genotype related issues, knowing your genotype will save you a great deal of issues.
It is no longer news to say that some genotype are clearly incompatible, I urge young people before going into marriage that they check up their genotype regardless of the love they claim to have for each other or even religious believes. This is because the sort of gene that runs through your spouse is not seen through love it can only be seen through adequate laboratory tests. To be sure of the genotype of your spouse or fiancé go for a test.
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Incompatibility of genes has been the reason why we have sickle cell outbreak all around the world, this severe blood complication called sickle cell has caused a lot of threats to life and has also hampered many love stories all around, it is very imperative we test to know our gene and that of our partners so as to keep them healthy and also produce healthy offspring. A large amount of children suffer from this severe complications which is passed unto them from the genes of their parent.
Genotype from the male and female merges during sexual and intercourse to produce another gene in the offspring, so both genes comes to play in the formation of an offspring, so as not to birth offspring with health complication we advise that only compatible gene get married.
Basically, there are five types of the hemoglobin genotypes which runs in human beings which are: AA, AS, AC, SS. The way it works is that in child production each person will donate a part of the hemoglobin gene that is, if the woman is AA she will donate A and if the man is SS he will donate S as that is what made up his gene.
Below is a list of marriageable genotypes
AA + AA (Excellent)
AA + AS (Good)
AA + SS (Fair)
AA + AC (Good)
AS + AS (Very Good)
AS + SS (Very Bad)
AS +AC (Bad Advice Needed)
SS + SS (Very Bad)
AC + SS (Very Bad)
AC + AC (Bad Advice Needed)
Getting married to a partner with a compatible genotype is necessary to kick out the spread of sickle cell anemia and given your children freedom choice on who to marry and also given them a chance of good health. Bone marrow transplant has been the only proven cure for SC, SS, and CC and it is very expensive and risky.
If you are getting married to your partner don’t get too entangled and forget about your genotype compatibility. It has killed a lot of promising children and talent and it has always been the fault of their parents.